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Effects of Non-Pharmacologic Interventions in Esophageal Cancer Surgery Patients: A Systematic Review and Meta-Analysis

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KMID : 1033320220120010001
±èÇýÁ¤ ( Kim Hye-Jung ) - Masan University Department of Nursing

¼­Áö¹Î ( Seo Ji-Min ) - Pusan National University College of Nursing
ÀÌÇýÁø ( Lee Hye-Jin ) - Pusan National University College of Nursing

Abstract

Purpose:This study aimed to investigate the effects of non-pharmacological interventions in esophageal cancer surgery patients via a systematic review and meta-analysis.

Methods: This study was conducted in April 2020 to update the original review. A systematic literature review was conducted based on the PubMed, EMBASE, CINAHL, CENTRAL, NDSL, RISS, KISS, and KMbase databases. Comprehensive Meta-Analysis (version 3.0) software was used to analyze the standard effect size, subgroup variables, and publication bias.

Results: In total, 10 of 17 studies were used to estimate the effect size of non-pharmacological interventions such as education, exercise, management (temperature control, pain control, etc.), and nutritional support. These non-pharmacological interventions were effective in improving the quality of life (g, 0.15; 95% confidence interval, 0.10~0.21). However, pneumonia and lung function remained unaffected. The subgroup analysis according to the intervention type showed that education was effective in improving the quality of life, and interventions comprising education, management, and nutritional support were effective in reducing the incidence of pneumonia.

Conclusion: In order to improve the quality of life and to prevent pneumonia in esophageal cancer surgery patients, non-pharmaceutical interventions comprising education, exercise, management, and nutritional support should be developed and provided.
KeyWords
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Esophageal neoplasms, Systematic review, Meta-analysis
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